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How safe is CBD oil?

MINNESOTA SPOKESMAN-RECORDER — From bath oils and soft drinks to skin creams and coffee bars, everywhere you look, you can see what looks like the next hot product: CBD oil.

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By Dr. Charles Crutchfield III MD

From bath oils and soft drinks to skin creams and coffee bars, everywhere you look, you can see what looks like the next hot product: CBD oil.

CBD, or cannabidiol, oil is a member of the cannabinoid family of molecules found in marijuana and plants closely related to marijuana, such as hemp. Although CBD has been around since the 1940s, CBD’s popularity has dramatically increased along with the legalization of medical and recreational marijuana across the United States.

There are over 100 different cannabinoids found in marijuana and hemp plants. CBD and tetrahydrocannabinol (THC) are the most commonly studied cannabinoids. CBD oil is extracted from the buds and flowers of marijuana and related plants, such as hemp. But, unlike THC, which is psychoactive marijuana derivative oil, CBD does not produce a “high” or intoxicated feeling.

CBD does have medicinal benefits, however. Proponents of CBD claim that it can treat a variety of conditions including seizures, pain, anxiety, inflammation, insomnia, acne and other skin diseases, and even some forms of cancer.

Experts are not quite as enthusiastic because solid scientific research has not verified most of these claims, yet. That has not stopped marketers and producers. In addition to CBD-infused products popping up in bath and body stores and local coffee shops, many malls now have “CBD stores” dedicated to selling a variety of products containing CBD oil. You can even search “CBD oil” on Amazon.com and well over 1,000 products are displayed – all touted to treat a wide variety of health concerns.

Read on to learn more about the different types of cannabinoids and safety and effectiveness of CBD.

Three types of cannabinoids

Phytocannabinoids

These compounds, like CBD, are found in plants like marijuana and hemp.

Endocannabinoids

These are found in the human body, discovered as a result of studying phytocannabinoids. They are derivatives of a chemical called arachidonic acid. Many tissues and organs contain receptors for endocannabinoids, which are released by human tissues in times of pain and inflammation. It is well-documented that receptors for endocannabinoids are located throughout the human body, including skin cells and the nervous system and brain.

The endocannabinoids in the skin can regulate cell growth which can be used in cancer treatments. The endocannabinoids in the nervous system and brain may affect thinking and understanding, memory, body movements, and pain control.

Synthetic cannabinoids

These are man-made cannabinoids used for research purposes and in some currently available products. They may eventually be employed in pharmacologic preparations and drug treatments used for cannabinoid-responsive conditions.

The rest of this column will focus on the phytocannabinoid, CBD.

Is CBD safe?

Unfortunately, most CBD is being produced without regulation. As a result, purity and quality can vary greatly.

In a recent study, 70 percent of products evaluated contained a different amount of CBD than listed on the label. Most products examined had less CBD, but some had more. Also, about 15 percent of CBD-containing products had measurable amounts of THC. This derivative can cause anxiety, just the very thing CBD is reported to calm, and THC should not be in CBD products.

Additionally, CBD is poorly absorbed. Only about 20 percent of CBD gets absorbed, so the quality and purity of CBD products are critical for their effectiveness.

Some studies have shown that CBD can have adverse effects on the liver. This seems to be the case in about five percent of all people. Other studies need to be done to see how CBD affects a person if the person consuming CBD is taking other medications. This is extremely important.

In general, there are relatively few side effects. So, the downside in using CBD-containing products is relatively low, but liver and other possible drug interactions must be considered.

Is CBD legal?

This is really a grey and ever-changing area. It appears to be legal in the 30+ states where marijuana is legal, but the overall national legal status has not been challenged yet, and the FDA has taken a very quiet and conservative stance.

Recently, a farm bill was proposed and is expected to pass that will make hemp-derived CBD legal. Keep in mind that just because something is legal does not mean that it is FDA-approved to treat anything or everything that is printed on the label.

Is CBD effective?

There are CBD receptors in our bodies. In the presence of bound CBD, our bodies can produce physiologic responses. In fact, CBD is FDA-approved to treat certain epileptic seizures in children.

There is emerging research that CBD may be useful in treating anxiety, and there are countless anecdotal reports that it helps muscle aches, joint pain, depression, psychiatric conditions, and insomnia. The number of human trials for other diseases is small but promising.

In fact, CBD’s use as an anti-inflammatory may be the next area for future FDA investigation and approval. As mentioned, many cells in our bodies have CBD receptors, so it stands to reason that CBD can have other physiologic effects in humans, such as on pain, inflammation, anxiety, and sleep.

Unfortunately, due to the murky legal status of CBD, research to uncover these physiologic responses has been sparse. As for other health claims, much more research, especially on humans rather than animals, needs to be done. Unfortunately, due to lack of regulation, manufacturers of products that contain CBD can print just about any health claim that they want on the product label, and buyers, desiring a relatively inexpensive, natural treatment, may just believe it.

As the new farm bill clears, legality issues over research should move forward at a much faster pace. Additionally, the best method of CBD delivery (oral, topical or inhaled) should be studied for the best treatment results.

Should I use CBD?

CBD is a promising product for a variety of challenging medical conditions, but more research needs to be done. If one is considering the use of CBD when other tried-and-true treatments are not working, don’t just buy something off the shelf because the label says it will help you.

I would strongly suggest using CBD-containing products with the guidance and care of a physician knowledgeable about and familiar with CBD-containing products. The future appears bright for CBD-containing products, but its ultimate success will depend on the production of high-quality products with safe, proven and approved results.

This article originally appeared in the Minnesota Spokesman-Recorder. 

Dr. Charles Crutchfield III MD

Black History

Doulas Are Helping Black California Moms Navigate Pregnancy–Even as High Mortality Rates Persist

In California, Black women experience the highest pregnancy-related mortality rate — about four times greater than other women, according to statistics. From 2021 to 2023, the leading causes of pregnancy-related deaths included cardiovascular disease, COVID-19, hemorrhage, sepsis, amniotic fluid embolism, and pulmonary embolism.

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Long Beach resident Cassandra Carter approached the birth of her daughter, Nyomi (pictured), last November with anxiety after losing twins. She is pictured here with her husband.

After losing twins, Long Beach resident Cassandra Carter approached the birth of her daughter, Nyomi, last November with anxiety. She wanted support for herself and her husband, Adewole, that extended beyond routine medical care. 

“Getting pregnant as a Black woman, I wanted a team around me that made me feel safe,” she said. “I know all about the mishaps that Black women experience.”  

Carter, a therapist and self-described hippie, hired Yvette Perry, a doula and co-founder of Divine Birthing Services LLC in Lancaster. Perry helped Cassandra craft a detailed birth plan. 

“I was worried about postpartum depression. Mrs. Yvette knows a lot about how postpartum affects men as well,” Carter explained. 

Perry was present the day Nyomi was born. She held the baby when Carter or her husband needed a moment and even set up candles in the birthing suite.  

“Whatever I needed for my comfort, she was there,” Carter said of Perry. “She was there as an advocate and voice. I had a really serene birthing experience because I had someone extra who wasn’t tied to me as my family.”  

Perry, a doula for nearly six years, said preexisting conditions, poor communication and dismissive hospital care heighten health risks for Black mothers. 

“Sometimes, Black mommies are not being heard. They don’t know they have rights. They don’t know they can say, ‘no,’” Perry explained. “Doulas empower them. We are there to educate them.” 

Perry’s concerns reflect a broader public health crisis. According to the Centers for Disease Control and Prevention’s 2024 maternal mortality report, non-Hispanic Black women in the U.S. died from pregnancy-related causes at a rate of 44.8 deaths per 100,000 live births. 

In California, Black women experience the highest pregnancy-related mortality rate — about four times greater than other women, according to statistics. From 2021 to 2023, the leading causes of pregnancy-related deaths included cardiovascular disease, COVID-19, hemorrhage, sepsis, amniotic fluid embolism, and pulmonary embolism. 

The Centering Black Mothers in California report found that structural racism — including barriers to high-quality health care, and chronic stress— disproportionately harms Black women. 

In a statement to California Black Media (CBM), the California Department of Public Health (CDPH) said maternal mortality disparities stem from multiple factors. The department said addressing structural racism, listening to Black women’s experiences and reducing provider bias are key to closing the gap. 

California began covering doula care as a Medi-Cal benefit in 2023, providing eligible patients with support during pregnancy, childbirth and the postpartum period, according to CDPH.  

Whitney Dotson of Inglewood wanted an expert on pregnancy, labor, and delivery to guide her and her husband, Anthony, through the birth of their son, Anthony III. So, she hired Perry for doula support. 

“It’s always more comfortable when you can have a second opinion,” she said. “Knowing she was better versed in what the options were, made me more comfortable.” 

Dotson, 39, had a healthy pregnancy but faced recommendations common for expectant mothers over 35. Her doctor advised inducing labor at 39 weeks, but she hoped to carry to full term. 

“I wasn’t comfortable with that,” she admitted. 

Perry provided Dotson with information about induction guidelines and alternatives, helping her understand her options and communicate her preferences.  

Then, Dotson returned to her doctor. 

“I said, ‘I don’t want to — and this is why,’” she recalled. “He agreed and pushed the induction date back a week.” 

Perry also advised Anthony on how he could support his wife during and after the pregnancy and during Anthony III’s birth. She also reminded Dotson to change birthing positions — from her back to her hands and knees.  

Before Saveneh Martinez became a doula with Fierce Advocates in Contra Costa County, she was a new mom, uneducated on aspects of birth, which led to her first child, Colton, being placed in a Neonatal Intensive Care Unit. 

“I didn’t know my choices,” she said.   

Martinez called it “lifesaving” for expecting moms to have a doula.  

“It should be a medical right,” she said.  

California Perinatal Quality Care Collaborative (CPQCC) Senior Associate Medical Director Kimberly D. Gregory said research suggests that doulas decrease the pre-term birth rate and the likelihood of a C-section.  

“Having a doula is a proactive thing to do,” she said.  

Efforts are being made across the state to reduce maternal deaths.  

CDPH’s Title V Action Plan aims to reduce pregnancy-related deaths among Black birthing mothers from 49.7 to 42.3 per 100,000 live births by 2030 through improvements in patient-centered care, expanding community-based perinatal teams, and addressing the social factors that contribute to poor maternal health outcomes. 

CDPH’s Black Infant Health (BIH) Program and Perinatal Equity Initiative (PEI) have already begun to make headway.  

“BIH’s prenatal group model improves key intermediate outcomes for participants, including increased social support and empowerment, better stress management, reduced depressive symptoms and gains in health knowledge and behaviors such as safe sleep practices and reduced smoking,” the CDPH told CBM.  

“PEI’s early implementation results show progress across several participant-reported areas, such as improved birth experiences, breastfeeding initiation, and coparenting skills among fathers and partners,” the CDPH statement continued.  

Gregory said the California Pregnancy Associated Review Committee examines maternal deaths and develops guidelines to help hospitals improve care. One of its main recommendations focuses on how hospitals respond to hemorrhaging, a leading cause of pregnancy-related deaths. 

Gregory said CMQCC also created standard clinic care practices for cardiovascular disease and sepsis, two more drivers of maternal mortality, but widespread implementation across the state is pending.  

She noted that although there are 800 maternal deaths a year in the U.S., there are also 3.6 million births.  

“Most people will do well,” she said. “But you should know about complications like preterm birth. You should know about complications like diabetes, preeclampsia and postpartum depression.” 

Martinez said doulas help to make birthing the transformative experience that it is, instead of a routine clinical transaction. 

“Being able to feel heard, seen, safe, respected, and just being able to create spaces for them to be held as well,” she said.  

Supported by the California Health Care Foundation (CHCF), which works to ensure that people have access to the care they need, when they need it, at a price they can afford. Visit www.chcf.org to learn more.

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Featured

On Your November Ballot: Prop 38 Would Allocate $8.4 Billion to Immunology and Immunotherapy Funding

“Yes on 38”, with the tagline “Californians for Life-Saving Immunology Research and Cures,” is leading the campaign for the support side of the proposition.

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California voters will decide in November whether Proposition (Prop) 38 should authorize substantial state funding for immunology and immunotherapy research.

The initiative would fund immunology and immunotherapy research aimed at harnessing the body’s immune system to develop new treatments, medical procedures and potential cures for diseases such as cancer, Alzheimer’s disease and heart disease.

More specifically, Prop 38, titled the Immunology and Immunotherapy Research Funding Initiative, is split into three main components that would go into effect if passed.

First, the initiative would authorize the state to issue $8.4 billion in general obligation bonds to support immunology and immunotherapy research. At least half of the bond proceeds, or $4.2 billion, would be dedicated exclusively to research.

Additionally, Prop 38 would make it mandatory for the state to enter into an agreement with a qualified nonprofit institute focused and dedicated to researching immunology and immunotherapy within 90 days of the initiative’s effective date. The research institute must be affiliated with the University of California. 

The third component mandates that the remaining bond revenue must be directed to California-based public and nonprofit medical institutions through a peer-reviewed grant process.  

“Yes on 38”, with the tagline “Californians for Life-Saving Immunology Research and Cures,” is leading the campaign for the support side of the proposition. 

Along with the campaign, organizations that have publicly supported the ballot initiative include the California Democratic Party, The ALS Association, Alzheimer’s treatment and advocacy organizations, California Black Health Network, Parkinson Association of Northern California and Reform California among others.

“California has an opportunity to accelerate lifesaving medical breakthroughs. Immunotherapies work differently than traditional treatments. Instead of attacking cells directly, they empower the body’s own immune system to recognize and stop disease. Today, these therapies are already treating certain cancers and chronic conditions — and researchers continue to expand what’s possible. This initiative invests in proven science so cures can move from the lab to patients faster,” said the campaign.

No on Proposition 38 is leading the campaign against the measure, with support from the League of Women Voters of California. Opponents argue that California cannot afford to assume $8.4 billion in debt for medical research that may not produce definitive results. They also object to directing more than half of the bond proceeds — $4.2 billion — to a single qualifying nonprofit research institute, arguing that funding decisions of this magnitude should be made through the state’s regular budget process.

“Medical research can save lives, but Prop 38 is the wrong way to fund it. It would authorize $8.4 billion in borrowing for immunology and immunotherapy research and require the state to make $500 million to $600 million in annual debt payments for about 20 years. Those payments would come from the General Fund, which also pays for schools, health care, and other public services,” the League of Women Voters of California said.

A “yes” vote would authorize $8.4 billion in state bonds to fund immunology and immunotherapy medical research.

A “no” vote would reject the proposed bond funding.

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Community

Two Looming Threats Every Alameda County Elder Should Know About

Federal changes enacted under H.R. 1 are bringing new eligibility, reporting, and coverage rules beginning in 2027. Although Californians age 65 and older and people with disabilities are exempt from the new 80-hour-per-month work requirement and will continue with annual rather than six-month renewals, that does not mean elders can ignore the coming changes.

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Alameda County elders are urged to attend the Elder Justice Symposium at Oakland City Hall on Sept. 25, from 9 a.m. to 5 p.m., for information that could profoundly affect both their health care and the legacy they hope to leave their families.

For many older adults, a lifetime of hard work has produced two things they understandably want to protect: access to health care while they are living and the home, savings, and other assets they hope to pass to loved ones when they die.

Changes already underway in California make understanding how to protect both increasingly urgent.

The first threat involves Medi-Cal.

Federal changes enacted under H.R. 1 are bringing new eligibility, reporting, and coverage rules beginning in 2027. Although Californians age 65 and older and people with disabilities are exempt from the new 80-hour-per-month work requirement and will continue with annual rather than six-month renewals, that does not mean elders can ignore the coming changes.

California has already reinstated an asset test for certain Medi-Cal recipients age 65 and older, people with disabilities and those needing long-term care. Assets must be reported when applying or renewing coverage.

And another significant change is coming.

Beginning July 1, 2027, California says the Medi-Cal asset limit for affected beneficiaries will fall from $130,000 for one person to just $21,000, and to $31,000 for two people, with certain assets excluded and special rules applying in some circumstances.

There is more. Beginning Jan. 1, 2027, Medi-Cal’s retroactive coverage period will also shrink. For most beneficiaries outside the ACA expansion adult group, coverage of qualifying medical expenses incurred before application will be reduced from three months to two.

For an elder facing hospitalization, long-term care or an unexpected medical crisis, misunderstanding these rules could have enormous financial consequences.

The second threat concerns what happens to everything you worked so hard to acquire.

Many people believe, “I have a will and a living trust, so my family is protected.”

It may not be that simple.

An estate plan is only as effective as the way it has been structured, maintained and implemented. How assets are titled, whether a trust has actually been funded, beneficiary designations, Medi-Cal eligibility and long-term-care planning can all affect whether a person’s wishes are ultimately carried out.

A will by itself does not automatically avoid probate, and simply possessing trust documents does not mean every asset has been properly protected or positioned to pass as intended.

That is why elders should learn the rules before a medical crisis, incapacity or death makes planning far more difficult.

At the Elder Justice Symposium, experts will explain these changes in understandable language and discuss steps that elders and their families should consider now.

Attendees will have an opportunity to learn what questions to ask about Medi-Cal eligibility and renewals, asset limits, estate planning and protecting the legacy they intend for their families.

Do not assume the rules you learned years ago are still the rules governing you today.

Come to Oakland City Hall on Sept. 25, from 9 a.m. to 5 p.m.

Bring your questions. Bring your family. Most importantly, bring a willingness to prepare.

The decisions you make before these changes take full effect could profoundly affect your health care, your financial security, and what remains for the people you love.

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