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How safe is CBD oil?

MINNESOTA SPOKESMAN-RECORDER — From bath oils and soft drinks to skin creams and coffee bars, everywhere you look, you can see what looks like the next hot product: CBD oil.

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By Dr. Charles Crutchfield III MD

From bath oils and soft drinks to skin creams and coffee bars, everywhere you look, you can see what looks like the next hot product: CBD oil.

CBD, or cannabidiol, oil is a member of the cannabinoid family of molecules found in marijuana and plants closely related to marijuana, such as hemp. Although CBD has been around since the 1940s, CBD’s popularity has dramatically increased along with the legalization of medical and recreational marijuana across the United States.

There are over 100 different cannabinoids found in marijuana and hemp plants. CBD and tetrahydrocannabinol (THC) are the most commonly studied cannabinoids. CBD oil is extracted from the buds and flowers of marijuana and related plants, such as hemp. But, unlike THC, which is psychoactive marijuana derivative oil, CBD does not produce a “high” or intoxicated feeling.

CBD does have medicinal benefits, however. Proponents of CBD claim that it can treat a variety of conditions including seizures, pain, anxiety, inflammation, insomnia, acne and other skin diseases, and even some forms of cancer.

Experts are not quite as enthusiastic because solid scientific research has not verified most of these claims, yet. That has not stopped marketers and producers. In addition to CBD-infused products popping up in bath and body stores and local coffee shops, many malls now have “CBD stores” dedicated to selling a variety of products containing CBD oil. You can even search “CBD oil” on Amazon.com and well over 1,000 products are displayed – all touted to treat a wide variety of health concerns.

Read on to learn more about the different types of cannabinoids and safety and effectiveness of CBD.

Three types of cannabinoids

Phytocannabinoids

These compounds, like CBD, are found in plants like marijuana and hemp.

Endocannabinoids

These are found in the human body, discovered as a result of studying phytocannabinoids. They are derivatives of a chemical called arachidonic acid. Many tissues and organs contain receptors for endocannabinoids, which are released by human tissues in times of pain and inflammation. It is well-documented that receptors for endocannabinoids are located throughout the human body, including skin cells and the nervous system and brain.

The endocannabinoids in the skin can regulate cell growth which can be used in cancer treatments. The endocannabinoids in the nervous system and brain may affect thinking and understanding, memory, body movements, and pain control.

Synthetic cannabinoids

These are man-made cannabinoids used for research purposes and in some currently available products. They may eventually be employed in pharmacologic preparations and drug treatments used for cannabinoid-responsive conditions.

The rest of this column will focus on the phytocannabinoid, CBD.

Is CBD safe?

Unfortunately, most CBD is being produced without regulation. As a result, purity and quality can vary greatly.

In a recent study, 70 percent of products evaluated contained a different amount of CBD than listed on the label. Most products examined had less CBD, but some had more. Also, about 15 percent of CBD-containing products had measurable amounts of THC. This derivative can cause anxiety, just the very thing CBD is reported to calm, and THC should not be in CBD products.

Additionally, CBD is poorly absorbed. Only about 20 percent of CBD gets absorbed, so the quality and purity of CBD products are critical for their effectiveness.

Some studies have shown that CBD can have adverse effects on the liver. This seems to be the case in about five percent of all people. Other studies need to be done to see how CBD affects a person if the person consuming CBD is taking other medications. This is extremely important.

In general, there are relatively few side effects. So, the downside in using CBD-containing products is relatively low, but liver and other possible drug interactions must be considered.

Is CBD legal?

This is really a grey and ever-changing area. It appears to be legal in the 30+ states where marijuana is legal, but the overall national legal status has not been challenged yet, and the FDA has taken a very quiet and conservative stance.

Recently, a farm bill was proposed and is expected to pass that will make hemp-derived CBD legal. Keep in mind that just because something is legal does not mean that it is FDA-approved to treat anything or everything that is printed on the label.

Is CBD effective?

There are CBD receptors in our bodies. In the presence of bound CBD, our bodies can produce physiologic responses. In fact, CBD is FDA-approved to treat certain epileptic seizures in children.

There is emerging research that CBD may be useful in treating anxiety, and there are countless anecdotal reports that it helps muscle aches, joint pain, depression, psychiatric conditions, and insomnia. The number of human trials for other diseases is small but promising.

In fact, CBD’s use as an anti-inflammatory may be the next area for future FDA investigation and approval. As mentioned, many cells in our bodies have CBD receptors, so it stands to reason that CBD can have other physiologic effects in humans, such as on pain, inflammation, anxiety, and sleep.

Unfortunately, due to the murky legal status of CBD, research to uncover these physiologic responses has been sparse. As for other health claims, much more research, especially on humans rather than animals, needs to be done. Unfortunately, due to lack of regulation, manufacturers of products that contain CBD can print just about any health claim that they want on the product label, and buyers, desiring a relatively inexpensive, natural treatment, may just believe it.

As the new farm bill clears, legality issues over research should move forward at a much faster pace. Additionally, the best method of CBD delivery (oral, topical or inhaled) should be studied for the best treatment results.

Should I use CBD?

CBD is a promising product for a variety of challenging medical conditions, but more research needs to be done. If one is considering the use of CBD when other tried-and-true treatments are not working, don’t just buy something off the shelf because the label says it will help you.

I would strongly suggest using CBD-containing products with the guidance and care of a physician knowledgeable about and familiar with CBD-containing products. The future appears bright for CBD-containing products, but its ultimate success will depend on the production of high-quality products with safe, proven and approved results.

This article originally appeared in the Minnesota Spokesman-Recorder

Dr. Charles Crutchfield III MD

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Community

Diabetes Continues to Largely Impact Low-Income Black and Brown Communities

Communities of color, particularly Black and Brown people, are amongst the most affected by Type 2 diabetes (T2D) due to socioeconomic status, cultural, and environmental factors. More than 38 million people in the US have diabetes, with up to 95% having Type 2 diabetes. While individuals aged 45 and older are typically the age range for those being diagnosed, more and more children and young adults are developing the chronic illness, according to the CDC.

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Dr. Kevin Peterson, vice president of Primary Care at the American Diabetes Association, said in an email that the environments where Black and Brown people historically live, such as areas of high carbohydrate diets, contribute to the prevalence of this illness.
Dr. Kevin Peterson, vice president of Primary Care at the American Diabetes Association, said in an email that the environments where Black and Brown people historically live, such as areas of high carbohydrate diets, contribute to the prevalence of this illness.

By Magaly Muñoz

Communities of color, particularly Black and Brown people, are amongst the most affected by Type 2 diabetes (T2D) due to socioeconomic status, cultural, and environmental factors.

More than 38 million people in the US have diabetes, with up to 95% having Type 2 diabetes. While individuals aged 45 and older are typically the age range for those being diagnosed, more and more children and young adults are developing the chronic illness, according to the CDC.

Of the 1 in 10 people with diabetes, 16.4% of Black people and 14.7% of Hispanic people make up the highest rates among different groups.

Dr. Kevin Peterson, vice president of Primary Care at the American Diabetes Association, said in an email that the environments where Black and Brown people historically live, such as areas of high carbohydrate diets, contribute to the prevalence of this illness.

But family history can also have a part to play in someone’s diagnosis. Although it is not always a determining factor, first-degree relatives, like parents, with Type 2 diabetes can increase someone’s risk of developing the same condition.

Doctors recommend that if there is that direct link, taking precautions such as a healthy diet and exercise can minimize or eliminate the chances of having T2D.

But Peterson also acknowledged that there can be difficulties with maintaining a healthy lifestyle for Black and Brown communities.

“It can be difficult in low-income communities to access healthy eating choices, and opportunities for activity can often be limited,” Peterson said. “Being creative in finding an activity that is available in your situation, finding a friend to assist you, and identifying healthy foods that you like and are available is a struggle worth taking on.”

Food deserts are one systemic factor in how people, especially low-income communities, develop chronic illnesses that can cause irreversible damage. These deserts are areas that lack easy accessibility to fresh and healthy food options.

Dr. Lloyd Stockey, MD, Internal Medicine at Kaiser Oakland Medical Center, said low-income people of color would be less susceptible to chronic illnesses like type 2 diabetes if they had more access to nutritious food.

“When you go into lower income areas or areas where people of color live, you typically see a lot of things that affect diabetes – tobacco, alcohol and fast food,” he said. “When you go out to other more affluent areas, you see more farmers’ markets, more boutique places to eat, and healthier choices. You don’t see all of that fast food.”

One of the most important things to do when talking to patients about their diagnosis, Stockey said, is meeting them where they are at. People come from all different walks of life whether that socioeconomic status, education levels, or willingness to listen to the problems they have that are contributing to their T2D.

He’s encountered patients who know exactly what the illness is, how they want to make lifestyle changes and who want to keep up with their medicine, but then there are many who are the complete opposite. These patients can be harder to get through to but no resource is left unturned for them.

Dr. Walter Acuña, MD, Internal Medicine at Kaiser Oakland Medical Center, said it’s also important to understand people’s cultures and upbringings. He understands that Latino and Black patients might be used to certain kinds of diets that are carb heavy, but added that making little changes can prevent people from having to give up the food they love.

Acuña also explained that lower income people often have time restraints or live in neighborhoods where they don’t feel safe taking a 30-minute walk. Exercising in the living room or watching online workout tutorials are excellent alternatives and can help to improve overall health.

T2D is a lifelong chronic illness but it doesn’t have to dictate someone’s life, doctors say. As long as you’re taking your prescribed medicine, watching what you eat and actively trying to make lifestyle changes, the long term risks, like liver or kidney problems, eyesight issues or early death, can be reduced.

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Bay Area

Congresswoman Lee Celebrates Federal Green Transportation Investments for California

OAKLAND, CA — Congresswoman Barbara Lee (CA-12) today celebrated the Department of Transportation’s (DOT) announcement of two grants for California to expand clean transportation infrastructure. The DOT announced that Bay Area Rapid Transit (BART) will receive over $14 million to install Level 2 EV charging ports at all BART-managed parking facilities for use by customers and community members.

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Congresswoman Barbara Lee
Congresswoman Barbara Lee

OAKLAND, CA — Congresswoman Barbara Lee (CA-12) today celebrated the Department of Transportation’s (DOT) announcement of two grants for California to expand clean transportation infrastructure. The DOT announced that Bay Area Rapid Transit (BART) will receive over $14 million to install Level 2 EV charging ports at all BART-managed parking facilities for use by customers and community members. The DOT also announced that the California Department of Transportation will receive $102 million for the West Coast Truck Charging and Fueling Corridor Project to deploy charging and hydrogen fueling stations for zero-emission medium- and heavy-duty vehicles along 2,500 miles of key freight corridors in California, Oregon, and Washington.

The transportation sector is the largest source of U.S. carbon emissions. According to the United Nations’ Intergovernmental Panel on Climate Change (IPCC), a 50 percent reduction in carbon must be achieved by 2050—and as much as a 91 percent decrease by 2100—to stay within the globally accepted goal of limiting the planet’s warming to 1.5 degrees Celsius.

“Today, I am excited to announce that BART has been selected to receive this critical federal funding to help expand mobility and end fossil fuel dependence,” said Congresswoman Lee. “It is especially important the first phase of the project will prioritize deployment at stations in or near disadvantaged communities. BART is an essential part of our public transit system, and these funds will improve transit for its riders in throughout the Bay Area.”

By installing chargers at BART stations that are close to multifamily housing, workplaces, medical facilities, schools, and retail, the project will support robust EV adoption across a wide range of socioeconomic groups and road users.

Furthermore, because of discriminatory policies, highways were built near and through Black and brown communities, making these communities much more vulnerable to chronic illnesses associated with disproportionate exposure to air pollution. A reduction in gas-powered cars will be especially beneficial to communities of color and low-income communities who have been disproportionately harmed by infrastructural and environmental injustices.

The West Coast Truck Charging and Fueling Corridor Project will enable the emissions-free movement of goods connecting major ports, freight centers, and agricultural regions between the U.S. borders with Mexico and Canada.

On this funding, Congresswoman Lee said: “This funding will go a long way toward not only combatting the climate crisis, but it will create good-paying jobs as well. I thank the Department of Transportation and the Biden-Harris administration for their continued commitment to a cleaner and healthier environment.”

Last year, alongside the California delegation, Congresswoman Lee sent a letter to DOT Secretary Pete Buttigieg urging support for the grant application of the West Coast Truck Charging and Fueling Corridor Project through the Bipartisan Infrastructure Law’s Charging and Fueling Infrastructure program.

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California Black Media

Gov. Newsom Rejects Plans to Expand Air-Quality Monitoring in Refineries

On Aug. 19, Gov. Gavin Newsom vetoed a bill aiming to expand the State’s air-quality monitoring system to include more refineries. Newsom cited concerns regarding local control and high implementation costs. State Sen. Lena Gonzalez (D-Long Beach) authored Senate Bill (SB) 674, legislation that required real-time air monitoring of nearby petroleum refineries to keep track of sites producing biofuel and other pollutants.

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Courtesy of Gov. Newsom’s Office
Courtesy of Gov. Newsom’s Office.

By Bo Tefu, California Black Media

On Aug. 19, Gov. Gavin Newsom vetoed a bill aiming to expand the State’s air-quality monitoring system to include more refineries.

Newsom cited concerns regarding local control and high implementation costs.

State Sen. Lena Gonzalez (D-Long Beach) authored Senate Bill (SB) 674, legislation that required real-time air monitoring of nearby petroleum refineries to keep track of sites producing biofuel and other pollutants. The bill would have required communities close to refineries such as Chevron Refinery in Richmond, to get notifications when pollutants were dangerously high, requiring local governments and state agencies to address the poor conditions.

Newsom stated that although the bill had good intentions, the state had no funding to reimburse the refineries for implementing the required systems. The proposed bill obligated refineries to cover the costs of implementing the air monitoring systems, paying various fees over multiple years. However, State officials were unable to secure funding that could help expand programs that monitor air quality in all the refineries.

Oscar Espino-Padron, a senior attorney at Earthjustice, confirmed that two air quality districts in the Bay Area and South Coast Air Quality Management District supported SB 674.

Espino-Padron argued that the air quality districts would be “empowered to implement measures and to exercise their discretion to tailor this monitoring program based on when it’s appropriate in their jurisdictions.”

“It’s really a setback, not only for air quality but also for community safety,” he said.

According to SB 674, a report by the American Lung Association indicated that all 19 refineries in California are located in counties that received failing grades for particulate matter pollution. Environmental groups argued that communities are being deprived of data and information that could help them take proper and timely precautions as well as protect their families from pollution caused by the refineries.

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